Article
A comprehensive model based on temporal dynamics of peripheral T cell repertoire for predicting post-treatment distant metastasis of nasopharyngeal carcinoma.
Cancer immunology, immunotherapy : CII - 1 Mar 2022
Zhang Yajing, Zhu Yujie, Wang Jiaqi, Xu Yi, Wang Zekun, Liu Yang, Di Xuebing, Feng Lin, Zhang Ye
Abstract excerpt
Many nasopharyngeal carcinoma (NPC) patients develop distant metastases after treatment, leading to poor outcomes. To date, there are no peripheral biomarkers suitable for all NPC patients to predict distant metastasis. Hence, we purposed to develop a noninvasive comprehensive model for predicting post-treatment distant metastasis of all NPC. Since T-cell receptor β chain (TCRB) repertoire has achieved prognostic...
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