Article
Clinical application of whole transcriptome sequencing for the classification of patients with acute lymphoblastic leukemia.
BMC cancer - 2 Aug 2021
Walter Wencke, Shahswar Rabia, Stengel Anna, Meggendorfer Manja, Kern Wolfgang, Haferlach Torsten, Haferlach Claudia
Abstract excerpt
BACKGROUND: Considering the clinical and genetic characteristics, acute lymphoblastic leukemia (ALL) is a rather heterogeneous hematological neoplasm for which current standard diagnostics require various analyses encompassing morphology, immunophenotyping, cytogenetics, and molecular analysis of gene fusions and mutations. Hence, it would be desirable to rely on a technique and an analytical workflow that allows...
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