Article
Single-Nucleotide Polymorphisms within the cps Loci: Another Potential Source of Clinically Important Genetic Variation for Streptococcus pneumoniae?
Infection and immunity - 15 Oct 2021
Brown Jeremy S
Abstract excerpt
The Streptococcus pneumoniae capsule is essential for disease pathogenesis, suggesting that even minor genetic changes within the cps locus could potentially have important consequences. Arends et al. (D. W. Arends, W. R. Miellet, J. D. Langereis, T. H. A. Ederveen, et al., Infect Immun 89:e00246-21, 2021, https://doi.org/10.1128/IAI.00246-21) have identified 79 different nonsynonymous single-nucleotide...
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