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Proteomic analysis and microRNA expression profiling of plasma‐derived exosomes in primary immune thrombocytopenia

1 Aug 2021

Abstract excerpt

Exosomes are released into extracellular fluids and have emerged as vital biological mediators in autoimmune diseases. Plasma-derived exosomes have been reported to take part in the pathogenesis of primary immune thrombocytopenia (ITP), but the protein and miRNA cargoes have not been entirely elucidated. Via proteomic analysis and RNA sequencing on plasma-derived exosomes from ITP patients and healthy controls,...

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PMID: 34337736
DOI: 10.1111/bjh.17720

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