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CDH12 as a Candidate Gene for Kidney Injury in Posterior Urethral Valve Cases: A Genome-wide Association Study Among Patients with Obstructive Uropathies

23 Apr 2021

Abstract excerpt

Posterior urethral valves (PUVs) and ureteropelvic junction obstruction (UPJO) are congenital obstructive uropathies that may impair kidney development. To identify genetic variants associated with kidney injury in patients with obstructive uropathy. We included 487 patients born in 1981 or later who underwent pyeloplasty or valve resection before 18 yr of age in the discovery phase, 102 PUV patients in a first...

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PMID: 34337522
DOI: 10.1016/j.euros.2021.04.001

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