Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hearing Screening Combined with Target Gene Panel Testing Increased Etiological Diagnostic Yield in Deaf Children.

Neural plasticity - 1 Jan 2021

Xie Le, Qiu Yue, Jin Yuan, Xu Kai, Bai Xue, Liu Xiao-Zhou, Wang Xiao-Hui, Chen Sen, Sun Yu

Abstract excerpt

Genetic testing is the gold standard for exploring the etiology of congenital hearing loss. Here, we enrolled 137 Chinese patients with congenital hearing loss to describe the molecular epidemiology by using 127 gene panel testing or 159 variant testing. Sixty-three deaf children received 127 gene panel testing, while seventy-four patients received 159 variant testing. By use of 127 gene panel testing, more...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Deafness
Share to Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hearing, Cochlea, Tinnitus, Genetics

Share to Hearing Loss, Sensorineural

Share to High-Throughput Nucleotide Sequencing

Share to Mass Screening

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 34335733
DOI: 10.1155/2021/6151973
PMCID: PMC8324351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hearing Screening Combined with Target Gene Panel Testing Increased Etiological Diagnostic Yield in Deaf Children.PMID 34335733Read ↗

Molecular diagnose of a large hearing loss population from China by targeted genome sequencing.Semantic proximity Read ↗

Genetic Screening of a Chinese Cohort of Children with Hearing Loss using a Next-Generation Sequencing PanelSemantic proximity Read ↗

Genetic screening of a Chinese cohort of children with hearing loss using a next-generation sequencing panel.Semantic proximity Read ↗

Deafness gene variations in a 1120 nonsyndromic hearing loss cohort: molecular epidemiology and deafness mutation spectrum of patients in Japan.Semantic proximity Read ↗

Targeted Next-Generation Sequencing Successfully Detects Causative Genes in Chinese Patients with Hereditary Hearing Loss.Semantic proximity Read ↗

Genetic Counseling of a Hearing-impaired Patient with Multiple Genetic Mutations.Semantic proximity Read ↗

Molecular etiology of hereditary deafness using next generation sequencing in northwest ChinaSemantic proximity Read ↗

Mutation analysis of GJB2, SLC26A4, GJB3 and mtDNA12SrRNA genes in 251 non-syndromic hearing loss patients in Fujian, China.Semantic proximity Read ↗

Molecular epidemiology of Chinese Han deaf patients with bi-allelic and mono-allelic GJB2 mutations.Semantic proximity Read ↗

Genetic testing involving 100 common mutations for antenatal diagnosis of hereditary hearing loss in Chongqing, China.Semantic proximity Read ↗

Targeted exon sequencing successfully discovers rare causative genes and clarifies the molecular epidemiology of Japanese deafness patients.Semantic proximity Read ↗

Next-Generation Sequencing Facilitates Genetic Diagnosis And Improves The Management Of Patients With Hearing Loss In Clinical PracticeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.