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Article

Targeted Next-Generation Sequencing Successfully Detects Causative Genes in Chinese Patients with Hereditary Hearing Loss.

Genetic testing and molecular biomarkers - 1 Nov 2016

Chen Siqi, Dong Cheng, Wang Qi, Zhong Zhen, Qi Yu, Ke Xiaomei, Liu Yuhe

Abstract excerpt

AIMS: We attempted to identify the genetic epidemiology of hereditary hearing loss among the Chinese Han population using next-generation sequencing (NGS). MATERIALS AND METHODS: The entire length of the genes GJB2, SLC26A4, and GJB3, as well as exons of 57 additional candidate genes were sequenced from 116 individuals suffering from hearing loss. RESULTS: Thirty potentially causative mutations from these 60...

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Identifiers

PMID: 27610647
DOI: 10.1089/gtmb.2016.0051

Genes

GJB2
GJB3
PCDH15
TECTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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