Article
Genetic testing involving 100 common mutations for antenatal diagnosis of hereditary hearing loss in Chongqing, China.
Medicine - 30 Apr 2021
Hu Hua, Zhou Peng, Wu Jiayan, Lei Wei, Wang Yang, Yang Ying, Liu Hailiang
Abstract excerpt
ABSTRACT: To understand the possible carrier status of genes associated with hereditary hearing loss (HHL) in the general population among local residents and to give genetic counseling for pregnant women.A total of 3541 subjects were recruited. We used multiplex PCR technology combined with next-generation sequencing technology to detect 100 hotspot mutations in 18 common deafness-related genes. The homozygous...
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