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Article

Using a public database of Neisseria gonorrhoeae genomes to detect mutations associated with zoliflodacin resistance.

The Journal of antimicrobial chemotherapy - 11 Oct 2021

Adamson Paul C, Lin Eric Y, Ha Sung-Min, Klausner Jeffrey D

Abstract excerpt

BACKGROUND: Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is an urgent global health threat. Zoliflodacin is a novel antibiotic undergoing clinical trials for the treatment of gonorrhoea. While there are limited data regarding zoliflodacin resistance in N. gonorrhoeae, three amino acid mutations have been associated with increased MICs of zoliflodacin. OBJECTIVES: To determine the prevalence of three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34324655
DOI: 10.1093/jac/dkab262
PMCID: PMC8521401

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