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Article

Preoperative detection of the TERT promoter mutations in papillary thyroid carcinomas.

Clinical endocrinology - 1 Nov 2021

Nakao Tomoe, Matsuse Michiko, Saenko Vladimir, Rogounovitch Tatiana, Tanaka Aya, Suzuki Keiji, Higuchi Miyoko, Sasai Hisanori, Sano Tsutomu, Hirokawa Mitsuyoshi, Miyauchi Akira, Kawakami Atsushi, Mitsutake Norisato

Abstract excerpt

OBJECTIVE: Telomerase reverse transcriptase promoter (TERT-p) mutations are strongly associated with tumour aggressiveness and worse prognosis in papillary thyroid carcinomas (PTCs). Since the TERT-p mutations have been reported to be subclonal, it is unclear how accurately they can be detected by preoperative fine-needle aspiration (FNA). The objective of this study was to analyse the concordance rate of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Share to Thyroid Cancer Diagnosis and Treatment

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Identifiers

PMID: 34322882
DOI: 10.1111/cen.14567

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