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Article

Single cell functional genomics reveals plasticity of subcutaneous white adipose tissue (WAT) during early postnatal development

21 Jul 2021

Abstract excerpt

OBJECTIVE: The current study addresses the cellular complexity and plasticity of subcutaneous (inguinal) white adipose tissue (iWAT) in mice during the critical periods of perinatal growth and establishment. METHODS: We performed a large-scale single cell transcriptomic (scRNA-seq) and epigenomic (snATAC-seq) characterization of cellular subtypes (adipose stromal cells (ASC) and adipocyte nuclei) during inguinal...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 34298199
DOI: 10.1016/j.molmet.2021.101307

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