Article
A graph centrality-based approach for candidate gene prediction for type 1 diabetes.
Immunologic research - 1 Oct 2021
Thummadi N B, Vishnu E, Subbiah E V, Manimaran P
Abstract excerpt
Type 1 diabetes mellitus (T1DM) or insulin-dependent diabetes is an autoimmune disease that may pose life-threatening situations to individuals. In most cases, cytotoxic T lymphocytes (CTLs) promotes killing of islets of Langerhans in the pancreas, which harbour insulin-producing beta cells. The trigger for autoimmune attack is still unclear; therefore, identifying and targeting candidate genes are imperative to...
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