Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of Early Feeding on Intestinal Permeability and Inflammation Markers in Infants with Genetic Susceptibility to Type 1 Diabetes: A Randomized Clinical Trial.

The Journal of pediatrics - 1 Nov 2021

Siljander Heli, Jason Eeva, Ruohtula Terhi, Selvenius Jenni, Koivusaari Katariina, Salonen Marja, Ahonen Suvi, Honkanen Jarno, Ilonen Jorma, Vaarala Outi, Virtanen Suvi M, Lähdeaho Marja-Leena, Knip Mikael

Abstract excerpt

OBJECTIVES: To assess whether weaning to an extensively hydrolyzed formula (EHF) decreases gut permeability and/or markers of intestinal inflammation in infants with HLA-conferred diabetes susceptibility, when compared with conventional formula. STUDY DESIGN: By analyzing 1468 expecting biological parent pairs for HLA-conferred susceptibility for type 1 diabetes, 465 couples (32 %) potentially eligible for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Defensins
Share to Caseins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Feeding Behavior

Share to Inflammation

Share to Intestinal Absorption

Share to Leukocyte L1 Antigen Complex

Share to Mannitol

Source

Identifiers

PMID: 34293372
DOI: 10.1016/j.jpeds.2021.07.042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of Early Feeding on Intestinal Permeability and Inflammation Markers in Infants with Genetic Susceptibility to Type 1 Diabetes: A Randomized Clinical Trial.PMID 34293372Read ↗

Early feeding and risk of type 1 diabetes: experiences from the Trial to Reduce Insulin-dependent diabetes mellitus in the Genetically at Risk (TRIGR).Semantic proximity Read ↗

Dietary intervention in infancy and later signs of beta-cell autoimmunity.Semantic proximity Read ↗

First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study.Semantic proximity Read ↗

Infant feeding in relation to islet autoimmunity and type 1 diabetes in genetically susceptible children: the MIDIA Study.Semantic proximity Read ↗

Do we need personalized recommendations for infants at risk of developing disease?Semantic proximity Read ↗

Term Infant Formula Supplemented with Human Milk Oligosaccharides (2′Fucosyllactose and Lacto‐N‐ neo tetraose) Shifts Stool Microbiota and Metabolic Signatures Closer to that of Breastfed InfantsSemantic proximity Read ↗

High Concentrations of Immunoglobulin G Against Cow Milk Proteins and Frequency of Cow Milk Consumption Are Associated With the Development of Islet Autoimmunity and Type 1 Diabetes-The Trial to Reduce Insulin-dependent Diabetes Mellitus (IDDM) in the Genetically at Risk (TRIGR) Study.Semantic proximity Read ↗

Role of Human Milk Bioactives on Infants' Gut and Immune HealthSemantic proximity Read ↗

Early infant feeding and risk of developing type 1 diabetes-associated autoantibodies.Semantic proximity Read ↗

Randomized feeding intervention in infants at high risk for celiac disease.Semantic proximity Read ↗

Introduction of gluten, HLA status, and the risk of celiac disease in children.Semantic proximity Read ↗

Randomized controlled trial on the influence of dietary intervention on epigenetic mechanisms in children with cow’s milk allergy: the EPICMA studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.