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Article

Dietary intervention in infancy and later signs of beta-cell autoimmunity.

The New England journal of medicine - 11 Nov 2010

Knip Mikael, Virtanen Suvi M, Seppä Karri, Ilonen Jorma, Savilahti Erkki, Vaarala Outi, Reunanen Antti, Teramo Kari, Hämäläinen Anu-Maaria, Paronen Johanna, Dosch Hans-Michael, Hakulinen Timo, Akerblom Hans K

Abstract excerpt

BACKGROUND: Early exposure to complex dietary proteins may increase the risk of beta-cell autoimmunity and type 1 diabetes in children with genetic susceptibility. We tested the hypothesis that supplementing breast milk with highly hydrolyzed milk formula would decrease the cumulative incidence of diabetes-associated autoantibodies in such children. METHODS: In this double-blind, randomized trial, we assigned 230...

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Identifiers

PMID: 21067382
DOI: 10.1056/NEJMoa1004809
PMCID: PMC4242902

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