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Article

BTF3-mediated regulation of BMI1 promotes colorectal cancer through influencing epithelial-mesenchymal transition and stem cell-like traits.

International journal of biological macromolecules - 30 Sept 2021

Zhou Wenli, Yun Zhennan, Wang Ting, Li Chao, Zhang Jiantao

Abstract excerpt

The critical roles of transcription factors in cell differentiation and the delineation of cell phenotypes have been reported. The current study aimed to characterize the functions of the basic transcription factor 3 (BTF3) gene and its regulation of the intestinal stem cell marker B cell-specific Moloney murine leukemia virus insertion site 1 (BMI1) gene in colorectal cancer (CRC). Stem cell-like traits and...

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PMID: 34293363
DOI: 10.1016/j.ijbiomac.2021.07.106

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