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Article

Circular RNA circSETD3 hampers cell growth, migration, and stem cell properties in bladder cancer through sponging miR-641 to upregulate PTEN.

Cell cycle (Georgetown, Tex.) - 1 Aug 2021

Tian Ying, Gao Ping, Dai Di, Chen Lan, Chu Xin, Mei Xuefeng

Abstract excerpt

Bladder cancer (BLCA) is a common malignant urothelial cancer in the world. Although circular RNAs (circRNAs) involve in regulating BLCA progression, the role of a novel circular RNA circSETD3 in regulating BLCA pathogenesis has not been studied. The expression of circSETD3, miR-641, PTEN mRNA in BLCA tissues and cell lines were measured using RT-qPCR. The gain-of-function experiments were performed in vitro and...

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Share to Cell Movement
Share to Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNAs

Share to Neoplasm Invasiveness

Share to Neoplastic Stem Cells

Share to PTEN Phosphohydrolase

Share to RNA, Circular

Share to Urinary Bladder Neoplasms

Source

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Identifiers

PMID: 34288821
DOI: 10.1080/15384101.2021.1954758
PMCID: PMC8409755

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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