Article
Multiple Genetically Distinct Uveal Melanomas Arise in the Same Eye of Two Patients with Melanosis Oculi.
American journal of ophthalmology - 1 Feb 2022
Wagley Sushant, Belin Peter J, Dollar James J, Harbour J William, Maltry Amanda C, Mruthyunjaya Prithvi, Schefler Amy C, Tang Peter H
Abstract excerpt
PURPOSE: To determine whether unilateral multifocal uveal melanomas (UM) in the setting of ocular melanosis (melanosis oculi) represent genetically independent tumors. DESIGN: Clinical case series. METHODS: Two patients with unilateral multifocal UM in the setting of melanosis oculi were included. Tumors were evaluated for gene expression profile (GEP) and next generation sequencing (NGS) for uveal...
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