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Article

Integrative miRNA and whole-genome analyses of epicardial adipose tissue in patients with coronary atherosclerosis.

Cardiovascular research - 1 Feb 2016

Vacca Michele, Di Eusanio Marco, Cariello Marica, Graziano Giusi, D'Amore Simona, Petridis Francesco Dimitri, D'orazio Andria, Salvatore Lorena, Tamburro Antonio, Folesani Gianluca, Rutigliano David, Pellegrini Fabio, Sabbà Carlo, Palasciano Giuseppe, Di Bartolomeo Roberto, Moschetta Antonio

Abstract excerpt

BACKGROUND: Epicardial adipose tissue (EAT) is an atypical fat depot surrounding the heart with a putative role in the development of atherosclerosis. METHODS AND RESULTS: We profiled genes and miRNAs in perivascular EAT and subcutaneous adipose tissue (SAT) of metabolically healthy patients without coronary artery disease (CAD) vs. metabolic patients with CAD. Compared with SAT, a specific tuning of miRNAs and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26645979
DOI: 10.1093/cvr/cvv266

Genes

CAD
CCL13

Provenance

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