Article
PhenoGeneRanker: Gene and Phenotype Prioritization Using Multiplex Heterogeneous Networks.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Dursun Cagatay, Kwitek Anne E, Bozdag Serdar
Abstract excerpt
Uncovering genotype-phenotype relationships is a fundamental challenge in genomics. Gene prioritization is an important step for this endeavor to make a short manageable list from a list of thousands of genes coming from high-throughput studies. Network propagation methods are promising and state of the art methods for gene prioritization based on the premise that functionally related genes tend to be close to...
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