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Article

The gene expression of GPER1 is low in fresh samples of papillary thyroid carcinoma (PTC), and in silico analysis.

Molecular and cellular endocrinology - 15 Sept 2021

Bertoni Ana Paula Santin, Manfroi Patrícia de Araujo, Tomedi Joelson, Assis-Brasil Beatriz Maria, de Souza Meyer Erika Laurini, Furlanetto Tania Weber

Abstract excerpt

Papillary thyroid cancer (PTC), whose incidence has been increasing in the last years, occurs more frequently in women. Experimental studies suggested that estrogen could be an important risk factor for the higher female incidence. In fact, it has been demonstrated that 17β-estradiol (E2) could increase proliferation and dedifferentiation in thyroid follicular cells. Genomic estrogen responses are typically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34273443
DOI: 10.1016/j.mce.2021.111397

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