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Article

Oestrogen receptor alpha in papillary thyroid carcinoma: association with clinical features and BRAFV600E mutation.

Japanese journal of clinical oncology - 1 Jul 2021

Liu Shiyang, Jiao Bo, Li Shuyu, Zhao Lu, Zheng Weihong, Wang Kun, Xu Jing, Tian Yao, Liu Chenguang, Gui Zhengwei, Zhang Lin

Abstract excerpt

BACKGROUND: Papillary thyroid cancer cells can express oestrogen receptor alpha, which is encoded by the ESR1 gene and may bind to oestrogen to induce the occurrence and development of papillary thyroid cancer. The BRAFV600E mutation is also an important biomarker for the occurrence and progression of papillary thyroid cancer. However, the association between the BRAFV600E mutation and oestrogen receptor alpha...

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Identifiers

PMID: 33893504
DOI: 10.1093/jjco/hyab058

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