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Article

Maternal Thyroid Hormone Programs Cardiovascular Functions in the Offspring.

Thyroid : official journal of the American Thyroid Association - 1 Sept 2021

Pedaran Mehdi, Oelkrug Rebecca, Sun Qian, Resch Julia, Schomburg Lutz, Mittag Jens

Abstract excerpt

Background: Maternal thyroid hormone (TH) plays an essential role for fetal development, especially for the cardiovascular system and its central control. However, the precise consequences of altered TH action during the different periods in pregnancy remain poorly understood. Methods: To address this question, we used mice heterozygous for a mutant thyroid hormone receptor α1 (TRα1) and wild-type controls that...

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Source

Identifiers

PMID: 34269617
DOI: 10.1089/thy.2021.0275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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