Article
Immunoglobulin GM and KM allotypes are associated with antibody responses to Pseudomonas aeruginosa antigens in chronically infected cystic fibrosis patients.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Nov 2021
Pandey Janardan P, Namboodiri Aryan M, Nietert Paul J, Knowles Michael R, Pace Rhonda G, Pier Gerald B
Abstract excerpt
BACKGROUND: Chronic infection with Pseudomonas aeruginosa (P. aeruginosa) is a leading cause of death in patients with cystic fibrosis (CF). Immunobiology of P. aeruginosa infection is complex and not well understood. Chronically infected CF patients generate high levels of antibodies to P. aeruginosa, but this response does not lead to clinical improvement. Therefore, additional studies aimed at identification...
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