Article
Early rise of anti-pseudomonas antibodies and a mucoid phenotype of pseudomonas aeruginosa are risk factors for development of chronic lung infection--a case control study.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Jan 2006
Pressler Tacjana, Frederiksen Birgitte, Skov Marianne, Garred Peter, Koch Christian, Høiby Niels
Abstract excerpt
P. aeruginosa is the most significant pathogen in CF lung disease. Chronic infection is preceded by a period of intermittent colonization. Early aggressive antimicrobial treatment at initial detection of P. aeruginosa in lower respiratory tract (LRT) secretions can prevent transition to chronic infection in approximately 80% of the patients, while the rest progress to chronic infection in spite of treatment. To...
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