The relationship between the rs4986791 variant of the TLR4 gene and the severity of bronchial asthma in children.

doi:10.12932/AP-100920-0954

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Article

The relationship between the rs4986791 variant of the TLR4 gene and the severity of bronchial asthma in children.

Asian Pacific journal of allergy and immunology - 1 Jun 2024

Chen Xiaoqing, Wang Kai, Yao Qin, Peng Lixin, Wei Lin

Abstract excerpt

BACKGROUND: Toll-like receptor 4 (TLR4) is an important receptor for lipopolysaccharide and lipid A, components of gram-negative bacteria. At present, a variant in TLR4 has been shown to be associated with asthma, but it has not been reported whether variants in TLR4 are associated with bronchial asthma in children. OBJECTIVE: The objective is to determine the relationship between the rs4986791 (+1196C/T)...

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PMID: 34246209
DOI: 10.12932/AP-100920-0954

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