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Article

Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model.

The Journal of infectious diseases - 1 Sept 2021

Abdelnabi Rana, Foo Caroline S, De Jonghe Steven, Maes Piet, Weynand Birgit, Neyts Johan

Abstract excerpt

The emergence of SARS-CoV-2 variants of concern (VoCs) has exacerbated the COVID-19 pandemic. Currently available monoclonal antibodies and vaccines appear to have reduced efficacy against some of these VoCs. Antivirals targeting conserved proteins of SARS-CoV-2 are unlikely to be affected by mutations arising in VoCs and should therefore be effective against emerging variants. We here investigate the efficacy of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34244768
DOI: 10.1093/infdis/jiab361
PMCID: PMC8408768

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