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Article

Prevalence of Naturally Occurring Resistance Associated Substitutions in NS3/4AProtease Inhibitors in Iranian HCV/HIV Infected Patients.

Current HIV research - 1 Jan 2021

Baesi Kazem, Velayati Ali Akbar, Ashtiani Masoumeh Farrokh, Fakhredini Kamal, Banifazl Mohammad, Larijani Mona Sadat, Basimi Parya, Ramezani Amitis

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) acts in the host as a complicated mixture of related variants with the potency to genetically escape host immune responses. Direct acting antivirals (DAAs) have been approved for HCV treatment with shorter duration, better cure rates and lower side effects. However, naturally occurring resistance associated substitutions (RASs) create some obstacles to this antiviral therapy...

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PMID: 34238162
DOI: 10.2174/1566523221666210707142838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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