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High prevalence of APOA1/C3/A4/A5 alterations in luminal breast cancers among young women in East Asia

5 Jul 2021

Abstract excerpt

In East Asia, the breast cancer incidence rate among women aged <50 years has rapidly increased. Emerging tumors are distinctly characterized by a high prevalence of estrogen receptor (ER)-positive/human epidermal growth factor receptor (HER2)-negative cancer. In the present study, we identified unique genetic alterations in these emerging tumors. We analyzed gene copy number variations (CNVs) in breast tumors...

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PMID: 34226567
DOI: 10.1038/s41523-021-00299-5

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