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In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission

5 Jul 2021

Abstract excerpt

Early events in retrovirus transmission are determined by interactions between incoming viruses and frontline cells near entry sites. Despite their importance for retroviral pathogenesis, very little is known about these events. We developed a bioluminescence imaging (BLI)-guided multiscale imaging approach to study these events in vivo. Engineered murine leukemia reporter viruses allowed us to monitor individual...

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PMID: 34223819
DOI: 10.7554/elife.64179

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