Article
Human inbreeding has decreased in time through the Holocene.
Current biology : CB - 13 Sept 2021
Ceballos Francisco C, Gürün Kanat, Altınışık N Ezgi, Gemici Hasan Can, Karamurat Cansu, Koptekin Dilek, Vural Kıvılcım Başak, Mapelli Igor, Sağlıcan Ekin, Sürer Elif, Erdal Yılmaz Selim, Götherström Anders, Özer Füsun, Atakuman Çiğdem, Somel Mehmet
Abstract excerpt
The history of human inbreeding is controversial.1 In particular, how the development of sedentary and/or agricultural societies may have influenced overall inbreeding levels, relative to those of hunter-gatherer communities, is unclear.2-5 Here, we present an approach for reliable estimation of runs of homozygosity (ROHs) in genomes with ≥3× mean sequence coverage across >1 million SNPs and apply this to 411...
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