Inflammation-related Proteins Support Diagnosis of Inflammatory Bowel Disease and Are Modified by Exclusive Enteral Nutrition in Children With Crohn's Disease, Especially of Ileal Phenotype.

doi:10.1093/ibd/izae107

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Inflammation-related Proteins Support Diagnosis of Inflammatory Bowel Disease and Are Modified by Exclusive Enteral Nutrition in Children With Crohn's Disease, Especially of Ileal Phenotype.

Inflammatory bowel diseases - 3 Mar 2025

White Bernadette, Svolos Vaios, Gervais Lisa, Jatkowska Aleksandra, Nichols Ben, MacDonald Jonathan, Seenan John Paul, Hansen Richard, Russell Richard K, Milling Simon, Gerasimidis Konstantinos

Abstract excerpt

BACKGROUND: The immunological effects of treatment with exclusive enteral nutrition (EEN) in Crohn's disease (CD) remain unknown. We characterized the plasma levels of inflammation-related proteins (IRPs) in children with CD and ulcerative colitis (UC) compared with noninflammatory controls (non-IBD) and explored the effect of EEN in CD. METHODS: Ninety-two IRPs were quantified using Olink proteomics in children...

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Topics

Humans
Enteral Nutrition
Female
Male
Crohn Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Child

Adolescent

Colitis, Ulcerative

Phenotype

Biomarkers

Ileum

Case-Control Studies

Inflammation

Proteomics

Source

Open in PubMed Open full text

Identifiers

PMID: 38920313
DOI: 10.1093/ibd/izae107
PMCID: PMC11879199

Genes

CCL23

Provenance

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