Article
Late Relapse and Reinfection in HCV Patients Treated with Direct-Acting Antiviral (DAA) Drugs.
Viruses - 16 Jun 2021
Minosse Claudia, Gruber Cesare E M, Rueca Martina, Taibi Chiara, Zaccarelli Mauro, Grilli Elisabetta, Montalbano Marzia, Capobianchi Maria R, Antinori Andrea, D'Offizi Gianpiero, McPhee Fiona, Garbuglia Anna Rosa
Abstract excerpt
The risk of hepatitis C virus (HCV) recurrence after direct-acting antiviral (DAA) treatment is <0.5%. However, the distinction between HCV RNA late relapse and reinfection still represents a challenge in virological diagnostics. The aim of this study was to employ next-generation sequencing (NGS) to investigate HCV RNA recurrence in patients achieving a sustained virologic response (SVR) at least six months...
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