Article
Dynamic changes of HCV genomes under selective pressure from DAAs therapy in relapsed patients.
Virus research - 1 Sept 2021
Deng Haohui, Guo Fengxia, Yu Weihua, Li Linghua, Xia Yang, Guan Yujuan, Li Jianping
Abstract excerpt
Currently, direct-acting antiviral drugs (DAAs) are widely used as therapeutic methods for hepatitis C virus (HCV)-positive patients, however, patients may experience treatment failure, and the dynamic changes of HCV genomes in these patients are unknown. In this study, three real-world DAAs cohorts were enrolled to observe clinical efficacy. In addition, serum samples from treatment failure patients at baseline...
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