Article
An inadequate dose of ribavirin is related to virological relapse by chronic hepatitis C patients treated with pegylated interferon alpha-2b and ribavirin.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Oct 2012
Ogawa Eiichi, Furusyo Norihiro, Kajiwara Eiji, Takahashi Kazuhiro, Nomura Hideyuki, Tanabe Yuichi, Satoh Takeaki, Maruyama Toshihiro, Nakamuta Makoto, Kotoh Kazuhiro, Azuma Koichi, Dohmen Kazufumi, Shimoda Shinji, Hayashi Jun
Abstract excerpt
The aim of this large-scale analysis was to assess the effect of 48-week pegylated interferon (PEG-IFN) α-2b and ribavirin (RBV) therapy on virological relapse by patients infected with hepatitis C virus (HCV) genotype 1. The relationship between virological relapse and the dose of PEG-IFNα-2b and RBV was investigated in 619 patients who had once cleared HCV RNA during PEG-IFNα-2b and RBV treatment for 48 weeks....
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