Article
Evidence of Circulation of Several HAV Genetic Variants and Emergence of Potential Antigenic Variants in an Endemo-Epidemic Country before Vaccine Introduction.
Viruses - 3 Jun 2021
Ayouni Kaouther, Chouikha Anissa, Khamessi Oussema, Touzi Henda, Hammemi Walid, Triki Henda
Abstract excerpt
Similar to several other countries in the world, the epidemiology of hepatitis A virus changed from high to intermediate endemicity level in Tunisia, which led to the occurrence of outbreaks. This study aimed to determine the genetic and antigenic variability of HAV strains circulating in Tunisia during the last few years. Genotyping using complete VP1 gene and VP1-2A junction confirmed the predominance of...
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