Article
Hepatitis A in Tunisia: phylogenetic analysis of hepatitis A virus from 2001 to 2004.
Journal of virological methods - 1 Dec 2006
Gharbi-Khelifi Hakima, Ferre Virginie, Sdiri Khira, Berthome Mathilde, Fki Lamia, Harrath Rafik, Billaudel Sylviane, Aouni Mahjoub
Abstract excerpt
Tunisia is a highly endemic area for hepatitis A virus (HAV) infection. In the present study, the phylogenetic characterization of the VP1 gene (882 nucleotides) and of the VP1/2A junction (336 nucleotides) of Tunisian strains were examined. One hundred strains isolated from patient with anti-HAV IgM from 2001 to 2004 were amplified by RT-PCR, sequenced at the VP1 and at the VP1/2A junction and aligned with the...
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