Article
Evolution and genetic characterization of hepatitis A virus isolates in China.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Apr 2015
Wang Hao, Wang Xin-Ying, Zheng Hui-Hui, Cao Jing-Yuan, Zhou Wen-Ting, Bi Sheng-Li
Abstract excerpt
OBJECTIVES: Hepatitis A virus (HAV), transmitted mainly through the fecal-oral route, is one of the major causes of acute viral hepatitis worldwide. HAV is endemic in China. This study performed genetic and evolutionary analysis of HAV isolates circulated in the country. METHODS: Clinical samples were collected and HAV nucleotide and deduced amino acid sequences were analyzed. 70 representative sequences of HAV...
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