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Article

Whole-Gene Deletions of FZD4 Cause Familial Exudative Vitreoretinopathy.

Genes - 27 Jun 2021

Huang Li, Lu Jinglin, Zhang Linyan, Zhang Zhaotian, Sun Limei, Li Songshan, Zhang Ting, Chen Limei, Cao Liming, Ding Xiaoyan

Abstract excerpt

Familial exudative vitreoretinopathy (FEVR) is an inherited disorder characterized by abnormalities in the retinal vasculature. The FZD4 gene is associated with FEVR, but the prevalence and impact of FZD4 copy number variation (CNV) on FEVR patients are unknown. The aim of this study was to better understand the genetic features and clinical manifestations of patients with FZD4 CNVs. A total of 651 FEVR families...

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Source

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Identifiers

PMID: 34199009
DOI: 10.3390/genes12070980
PMCID: PMC8306649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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