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Article

Molecular Characterization of FZD4, LRP5, and TSPAN12 in Familial Exudative Vitreoretinopathy.

Investigative ophthalmology & visual science - 1 Aug 2015

Seo Soo Hyun, Yu Young Suk, Park Sung Wook, Kim Jeong Hun, Kim Hyun Kyung, Cho Sung Im, Park Hyunwoong, Lee Seung Jun, Seong Moon-Woo, Park Sung Sup, Kim Ji Yeon

Abstract excerpt

PURPOSE: Familial exudative vitreoretinopathy (FEVR) is a rare hereditary disorder characterized by the failure of peripheral retinal vascularization. The genes FZD4, LRP5, and TSPAN12 are known to be associated with the autosomal inheritance form of FEVR. In this study, we performed mutation screening for FZD4, LRP5, and TSPAN12 in patients with clinical diagnosis of FEVR. In patients with no mutation detected,...

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Source

Identifiers

PMID: 26244290
DOI: 10.1167/iovs.14-15680

Genes

FZD4
LRP5
TSPAN12
ATOH7
NDP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular Characterization of FZD4, LRP5, and TSPAN12 in Familial Exudative Vitreoretinopathy.PMID 26244290Read ↗

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