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Article

MTHFR C677T Polymorphism and Serum Homocysteine Level as Risk Factors of Coronary Heart Disease in Patients with Androgenetic Alopecia: A Case Control Study.

The American journal of the medical sciences - 1 Oct 2021

Saafan Fawzia A, Elsamanoudy Ayman Z, Shaalan Dalia, Zeidan Nanees, Gaballah Mohammad A

Abstract excerpt

BACKGROUND: Androgenetic alopecia (AGA) is associated with a risk of coronary heart disease (CHD), although the causes underlying this association are not clear. Serum homocysteine (SH) is a known risk factor for CHD, and methylene tetrahydrofolate reductase enzyme (MTHFR) plays a crucial role in the remethylation of homocysteine to methionine. The polymorphism C677T that affects the catalytic domain of the MTHFR...

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PMID: 34192512
DOI: 10.1016/j.amjms.2021.06.013

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