Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation

1 Jun 2021

Abstract excerpt

Abstract Extracellular vesicles (EVs) are important players in cell to cell communication in reproductive systems. Notably, EVs have been found and characterized in the male reproductive tract, however, direct functional evidence for their importance in mediating sperm function is lacking. We have previously demonstrated that Arrdc4, a member of the α‐arrestin protein family, is involved in extracellular vesicle...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Reproductive System and Pregnancy
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34188787
DOI: 10.1002/jev2.12113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturationPMID 34188787Read ↗

ARRDC5 expression is conserved in mammalian testes and required for normal sperm morphogenesisSemantic proximity Read ↗

Roles of male reproductive tract extracellular vesicles in reproductionSemantic proximity Read ↗

Disruption of TEX38 impairs sperm morphogenesis and the migration of sperm into the oviductSemantic proximity Read ↗

Epididymal cysteine-rich secretory proteins are required for epididymal sperm maturation and optimal sperm functionSemantic proximity Read ↗

Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4Semantic proximity Read ↗

The repertoire of testicular extracellular vesicles cargoes and their involvement in inter-compartmental communication required for spermatogenesisSemantic proximity Read ↗

Relevance of CRISP proteins for epididymal physiology, fertilization, and fertilitySemantic proximity Read ↗

The molecular mechanisms underlying acrosome biogenesis elucidated by gene-manipulated mice†Semantic proximity Read ↗

Control of Membrane Fusion During Spermiogenesis and the Acrosome Reaction1Semantic proximity Read ↗

Unlocking Gamete Quality Through Extracellular Vesicles: Emerging PerspectivesSemantic proximity Read ↗

Sperm acquire epididymis-derived proteins through epididymosomesSemantic proximity Read ↗

Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity†Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.