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Genetic Characterization of Cancer of Unknown Primary Using Liquid Biopsy Approaches

10 Jun 2021

Abstract excerpt

Cancers of unknown primary (CUPs) comprise a heterogeneous group of rare metastatic tumors whose primary site cannot be identified after extensive clinical–pathological investigations. CUP patients are generally treated with empirical chemotherapy and have dismal prognosis. As recently reported, CUP genome presents potentially druggable alterations for which targeted therapies could be proposed. The paucity of...

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PMID: 34178989
DOI: 10.3389/fcell.2021.666156

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