Article
Effect of polymorphisms of endothelial nitric oxide synthase on ischemic stroke: a case-control study in a Chinese population.
Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2008
Cheng Jinquan, Liu Jianping, Li Xiaoxia, Yu Lei, Peng Ji, Zhang Renli, Geng Yijie, Nie Shaofa
Abstract excerpt
BACKGROUND: Nitric oxide (NO) synthesized by endothelial nitric oxide synthase (eNOS) plays a key role in vascular regulation and atherosclerosis, therefore, eNOS may be a candidate gene for ischemic stroke (IS). However, it is still controversial whether eNOS polymorphisms are a risk factor for IS. METHODS: Three polymorphisms of the eNOS gene (-922A/G, -786T/C, 894G/T) were determined by using TaqMan SNP...
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