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Article

Establishment and characterization of NCC-ssRMS2-C1: a novel patient-derived cell line of spindle cell/sclerosing rhabdomyosarcoma.

Human cell - 1 Sept 2021

Tsuchiya Ryuto, Yoshimatsu Yuki, Noguchi Rei, Sin Yooksil, Ono Takuya, Sei Akane, Takeshita Fumitaka, Sugaya Jun, Nakatani Fumihiko, Yoshida Akihiko, Ohtori Seiji, Kawai Akira, Kondo Tadashi

Abstract excerpt

Spindle cell/sclerosing rhabdomyosarcoma (ssRMS) is a rare subtype of rhabdomyosarcoma (RMS) that has fascicular spindle cell and/or sclerosing morphology. SsRMS has a diverse molecular background and is categorized into three groups: congenital/infantile ssRMS with a gene fusion involving the NCOA2 and VGLL2, ssRMS with the MYOD1 mutation, and ssRMS with no recurrent identifiable genetic alterations. Because...

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PMID: 34164773
DOI: 10.1007/s13577-021-00569-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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