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Article

Genetic variant effect prediction by supervised nonnegative matrix tri-factorization.

Molecular omics - 11 Oct 2021

Arani Asieh Amousoltani, Sehhati Mohammadreza, Tabatabaiefar Mohammad Amin

Abstract excerpt

Discriminating between deleterious and neutral mutations among numerous non-synonymous single nucleotide variants (nsSNVs) that may be observed through whole exome sequencing (WES) is considered a great challenge. In this regard, many machine learning methods have been developed for the prediction of variant consequences based on the analysis of either protein amino acid sequences or protein structures or their...

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PMID: 34164638
DOI: 10.1039/d1mo00038a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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