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Article

Inferring Crohn's disease association from exome sequences by integrating biological knowledge.

BMC medical genomics - 12 Aug 2016

Jeong Chan-Seok, Kim Dongsup

Abstract excerpt

BACKGROUND: Exome sequencing has been emerged as a primary method to identify detailed sequence variants associated with complex diseases including Crohn's disease in the protein-coding regions of human genome. However, constructing an interpretable model for exome sequencing data is challenging because of the huge diversity of genomic variation. In addition, it has been known that utilizing biologically relevant...

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Identifiers

PMID: 27535358
DOI: 10.1186/s12920-016-0189-2
PMCID: PMC4989895

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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