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The liver X receptor agonist LXR 623 restricts flavivirus replication

1 Jan 2021

Abstract excerpt

The vector-borne flaviviruses (VBFVs) are well known for causing great misery and death in humans worldwide. The VBFVs include those transmitted by mosquitos, such as Zika virus (ZIKV), dengue virus; and those transmitted by ticks including the tick-borne flavivirus serocomplex and Powassan virus (POWV). Two of our recent reports showed that intracranial POWV infection in the reservoir host, Peromyscus leucopus,...

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PMID: 34162308
DOI: 10.1080/22221751.2021.1947749

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