Fast and Accurate Algorithms for Mapping and Aligning Long Reads.

Abstract excerpt

For DNA sequence analysis, we are facing challenging tasks such as the identification of structural variants, sequencing repetitive regions, and phasing of alleles. Those challenging tasks suffer from the short length of sequencing reads, where each read may cover less than 2 single nucleotide polymorphism (SNP), or less than two occurrences of a repeated region. It is believed that long reads can help to solve...

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