Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BACH1 Binding Links the Genetic Risk for Severe Periodontitis with ST8SIA1.

Journal of dental research - 1 Jan 2022

Chopra A, Mueller R, Weiner J, Rosowski J, Dommisch H, Grohmann E, Schaefer A S

Abstract excerpt

Genome-wide association studies identified various loci associated with periodontal diseases, but assigning causal alleles remains difficult. Likewise, the generation of biological meaning underlying a statistical association has been challenging. Here, we characterized the genetic association at the gene ST8SIA1 that increases the risk for severe periodontitis in smokers. We used CRISPR/dCas9 activation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome-Wide Association Study
Share to Alleles
Share to Basic-Leucine Zipper Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Periodontitis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Sialyltransferases

Source

Open in PubMed Open full text

Identifiers

PMID: 34160287
DOI: 10.1177/00220345211017510
PMCID: PMC8721550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BACH1 Binding Links the Genetic Risk for Severe Periodontitis with ST8SIA1.PMID 34160287Read ↗

Periodontitis Risk Variants at SIGLEC5 Impair ERG and MAFB Binding.Semantic proximity Read ↗

Genetic analysis of cis-enhancers associated with bone mineral density and periodontitis in the gene SOSTSemantic proximity Read ↗

Integrative genomic analysis of 21 orofacial diseases identifies shared genetic architecture with systemic diseases.Semantic proximity Read ↗

Combined periodontitis GWAS identifies LINC01541 as a regulator of innate immunity in the oral mucosa.Semantic proximity Read ↗

Multi-Omics Integration Reveals the Genetic Mechanisms of Periodontitis and Predicts Therapeutic Drugs.Semantic proximity Read ↗

Genetics of periodontitis: Discovery, biology, and clinical impact.Semantic proximity Read ↗

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.Semantic proximity Read ↗

Genome-wide Association Study Identifies Novel Risk Loci for Apical Periodontitis.Semantic proximity Read ↗

Exome Sequencing of 5 Families with Severe Early-Onset Periodontitis.Semantic proximity Read ↗

Regulatory elements and genetic variations in periodontal diseases.Semantic proximity Read ↗

RETRACTED: Integrative Bioinformatics Analysis of m1A Genes in Periodontitis and Diabetes: Identifying Potential Diagnostic BiomarkersSemantic proximity Read ↗

Genetic Loci Associated With Periodontitis: The FinnGen Study Based on National Health Registers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.