Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/β-Catenin Signaling

22 Jun 2021

Abstract excerpt

Abstract Arginyltransferase (ATE1) plays critical roles in many biological functions including cardiovascular development, angiogenesis, adipogenesis, muscle contraction, and metastasis of cancer. However, the role of ATE1 in hepatocellular carcinoma (HCC) remains unknown. In this study, we find that ATE1 plays an essential role in growth and malignancy of liver cancer. ATE1 expression is significantly reduced in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Renin-Angiotensin System Studies
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34158395
DOI: 10.1158/1541-7786.mcr-21-0027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/β-Catenin SignalingPMID 34158395Read ↗

WNT/β‐catenin signaling in liver health and diseaseSemantic proximity Read ↗

KDM5B drives acute liver injury by impairing autophagy and activating cGAS-STING signaling via binding to ATG16L1Semantic proximity Read ↗

Identification of ETV5 as a prognostic marker related to epigenetic modification in pan-cancer and facilitates tumor progression in hepatocellular carcinomaSemantic proximity Read ↗

Long Noncoding RNAs Associated With Liver Regeneration 1 Accelerates Hepatocyte Proliferation During Liver Regeneration By Activating Wnt/β-Catenin SignalingSemantic proximity Read ↗

CGREF1 facilitates the cell proliferation, migration and invasion of hepatocellular carcinoma cells via regulation of EIF3H/ Wnt/β-Catenin signaling axisSemantic proximity Read ↗

ETV4 mediates the Wnt/β-catenin pathway through transcriptional activation of ANXA2 to promote hepatitis B virus-associated liver hepatocellular carcinoma progressionSemantic proximity Read ↗

FAT4 loss initiates hepatocarcinogenesis through the switching of canonical to noncanonical WNT signaling pathwaysSemantic proximity Read ↗

Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/β-Catenin SignalingSemantic proximity Read ↗

CTSG Suppresses Colorectal Cancer Progression through Negative Regulation of Akt/mTOR/Bcl2 Signaling PathwaySemantic proximity Read ↗

The role of lncRNA MALAT1 in the regulation of hepatocyte proliferation during liver regenerationSemantic proximity Read ↗

Discs large homolog 5 decreases formation and function of invadopodia in human hepatocellular carcinoma via Girdin and Tks5Semantic proximity Read ↗

Loss of hepatic Lgr4 and Lgr5 promotes nonalcoholic fatty liver diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.